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Introduction to Biochemical Sensors

Maastricht Summer School
Netherlands, Maastricht
Maastricht Summer School Netherlands, Bonnefantenstraat 2, 6211 KL Maastricht, The Netherlands
Tuition fee €699 one-time
More information



Course Description
This interdisciplinary course offers an introduction to the fascinating world of biochemical sensors, exploring key technologies and applications. Designed for students with diverse backgrounds in the realm of biotechnology and engineering this course provides a comprehensive overview of various biosensor types.
Course Content:
Module 1: Fundamentals of Biochemical Sensors
Basic principles of chemistry and biology relevant to sensor technologies.
Module 2: Sensor Technologies and Types
In-depth exploration of biosensors, biochemical sensors, paper-based sensors, fluorescent sensors, wearable sensors, implantable sensors, lab-on-a-chip technologies, and theragnostic.
Module 3: Applications and Clinical Trials
Practical applications of biochemical sensors in real-world scenarios, including insights into clinical trials.

• Apply scientific principles of chemical engineering to conceptually develop industry-standard biochemical devices and biotherapeutic systems, gaining a profound understanding of their limitations.
• Identify key nano/microfabrication methods used in analytical devices and biotherapeutic systems.
• Critically evaluate techniques and technologies in biosensing methods, fostering problem-solving skills for innovative product design.
• Investigate new methods to develop quantitative approaches for interpreting and analysing biodevices.
• Demonstrate an understanding of the characteristics and performance of biodevices, enabling the design of products and discussion of practical applications in the biotechnology industry.
• Explain systems and the fabrication of devices for targeted analyte monitoring, understanding specifications development in materials, system integration, and innovative product design.
• Demonstrate a comprehensive understanding of original research, encompassing emerging concepts, strategic approaches, and the evaluation of the potential impact of these emerging biotechnologies.

Recommended Literature
Paper-based microfluidic point-of-care diagnostic devices. Lab Chip, 13 (12), 2210-2251 (2013)
Andersson H, Van Den Berg A. Microfabrication and microfluidics for tissue engineering. Lab on a Chip 4(2):98-103 (2004)
Hendi A, Umair Hassan M, Elsherif M, Alqattan B, Park S, Yetisen AK, et al. Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review. International Journal of Nanomedicine. 2020
Jiang N, Mück JE, Yetisen AK. The Regulation of Wearable Medical Devices. Trends Biotechnol. 2020;38(2)
Syed AJ, Anderson JC. Applications of bioluminescence in biotechnology and beyond. Chem Soc Rev. 2021;50(9)
Barreiros dos Santos M, Rodriguez-Lorenzo L, Queirós R, Espiña B. Fundamentals of Biosensors and Detection Methods. In: Caballero D, Kundu SC, Reis RL, editors. Microfluidics and Biosensors in Cancer Research: Applications in Cancer Modeling and Theranostics. Cham: Springer International Publishing; 2022. p. 3-29.
Prabowo BA, Cabral PD, Freitas P, Fernandes E. The Challenges of Developing Biosensors for Clinical Assessment: A Review. Chemosensors. 2021;9(11)
Rodrigues D, Barbosa AI, Rebelo R, Kwon IK, Reis RL, Correlo VM. Skin-Integrated Wearable Systems and Implantable Biosensors: A Comprehensive Review. Biosensors (Basel). 2020;10(7)
Perumal V, Hashim U. Advances in biosensors: Principle, architecture and applications. J Appl Biomed. 2014;12(1):1-15

Teaching Methods
Assignments, Lectures, Papers ▪ PBL, Presentations, Skills, Work in subgroups

Learning Approach:
Emphasis on interactive learning, including group projects and mentorship sessions. Q&A sessions to facilitate in-depth understanding. Practical applications explored through real-world case studies. Closing day presentations to encourage knowledge sharing and collaborative learning.

Assessment Methods
Assignment, Attendance, Observation, Oral exam, Participation, Portfolio, Presentation

Course Coordinator
Eleni Chatzilakou

Programme structure

Course Structure:
The course spans one week, totalling 19 hours, with the following daily schedule:
Day 1:
Three-hour introductory session covering fundamental concepts.
Days 2-4:
Four-hour sessions with the first two hours delving into specific sensor technologies. The latter two hours will be dedicated to group projects, mentorship, and Q&A sessions.
Final Day:
Closing lecture summarizing key learnings.
Presentations from student groups showcasing their projects and insights.
Feedback sessions and Q&A related to the presentations.

Apply now! Maastricht Summer School 2023/24
Application deadline
8 Jun 2024, 23:59:59
Central European Time
Studies commence
8 Jul 2024
Apply now! Maastricht Summer School 2023/24
Application deadline
8 Jun 2024, 23:59:59
Central European Time
Studies commence
8 Jul 2024